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          GeneLooper™ 2.0: High-Throughput Utilities

Translation and Reverse Complement

Objective: 1. Translate mRNA sequences into protein sequences. 2. generate reverse complement strand (an accessory function) .

Determination and translation of the coding regions of mRNA sequences are important steps in the processes of gene annotation and gene mining since protein sequences are rich in information which may lead to the clues about the biological functions of a protein. For example, conserved domains are derived from protein sequences. The ability to directly translate multiple DNA sequences into proteins using a PC gives researchers advantage in studying a large number of genes.

Features:


1. Translate thousands of sequences in a short period of time.
2. Multiple ways to translate: direct translation, translation of the longest ORF and translation of all three frames.
3. Instant data report on protein lengths and molecular weights.
4. Translated protein sequences are saved in a Q-fasta file.

A sample of working interface:

 
Single Sequence Utilities

High-Throughput Utilities
  • Sequence Formatting
  • Sequence Collection
  • Sequence Separation
  • Sequence Retrieving
  • Open Reading Frame Detection
  • Sequence Clustering
  • Multi-Sequence Similarity Search
  • Restriction Site Search
  • Translation and Reverse Complement
  • Hydrophobic Domain Detection
  • Batch Oligo Design
  • Entrez Information Extraction

  •  

    Translation1

    Samples of the summary of a translation process:

    Translation2

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